Pilot trial of time restricted eating to support an adaptive innovative clinical trial of combined chronotherapies for mania in bipolar disorder

在躁狂发作期间，睡眠-觉醒周期被严重扰乱。通常躁狂症是用药物治疗的，这些药物可能会产生严重的副作用。多年来，患者和家属与这一人群的接触显示出对治疗的极大兴趣，

The sleep-wake cycle is severely disrupted during an episode of mania. Often mania is treated with medications that can come with significant side effects. Years of patient and family engagement with this population have revealed great interest in therapi