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Improving myoblast transplantation outcomes via pharmacological reprogramming: stimulation of C/EBPbeta expression maintains stem cell identity

Improving myoblast transplantation outcomes via pharmacological reprogramming: stimulation of C/EBPbeta expression maintains stem cell identity
通过药理学重编程改善成肌细胞移植结果:刺激 C/EBPbeta 表达维持干细胞身份
批准号:
351810
负责人:
Wiper-Bergeron Nadine L
金额:
$7.29万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-04-01 至 2017-04-01

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中文摘要
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英文摘要
One way to cure Duchenne muscular dystrophy (DMD) is to use stem cells to repair muscle. These stem cells, called satellite cells, can restore dystrophin expression to DMD muscle, reversing the muscle mass loss and weakness. However, when we isolate healt
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Glucocorticoid signalling in regenerating muscle: Mechanisms behind wasting side effects in healthy muscle and paradoxical benefit in Duchenne Muscular Dystrophy treatment.
  • 批准号:
    434367
  • 项目类别:
    Operating Grants
  • 资助金额:
    $63.25万
  • 财政年份:
    2020
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    Wiper-Bergeron Nadine L
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Regulation of muscle satellite cell self-renewal and differentiation by CCAAT/Enhancer Binding Protein beta: Implications in disease pathogenesis.
  • 批准号:
    342764
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    Operating Grants
  • 资助金额:
    $41.77万
  • 财政年份:
    2016
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    Wiper-Bergeron Nadine L
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A new role for CCAAT/Enhancer Binding Protein beta: inhibition of muscle satellite cell differentiation in cancer cachexia.
  • 批准号:
    226223
  • 项目类别:
    Operating Grants
  • 资助金额:
    $56.3万
  • 财政年份:
    2011
  • 负责人:
    Wiper-Bergeron Nadine L
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A new role for CCAAT/Enhancer Binding Protein beta: inhibition of muscle satellite cell differentiation in cancer cachexia.
  • 批准号:
    220189
  • 项目类别:
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  • 资助金额:
    $7.29万
  • 财政年份:
    2010
  • 负责人:
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