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The Modulation of R263K-Mediated HIV-1 Resistance to Integrase Strand Transfer Inhibitors by Acetylation.

The Modulation of R263K-Mediated HIV-1 Resistance to Integrase Strand Transfer Inhibitors by Acetylation.
通过乙酰化调节 R263K 介导的 HIV-1 对整合酶链转移抑制剂的抗性。
批准号:
347939
负责人:
Anstett Kaitlin
金额:
$7.65万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2015
资助国家:
加拿大
项目状态:
已结题
起止时间:
2015-10-01 至 2018-10-01

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中文摘要
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英文摘要
Although antiretroviral therapy has been lifesaving for many HIV-positive individuals, drug resistance threatens its long-term efficacy.Integrase (IN) is a HIV protein that is essential for the HIV lifecycle. Though HIV can develop resistance to the first
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Investigation of the sequential development of integrase strand transfer inhibitor resistance mutations in HIV.
  • 批准号:
    324345
  • 项目类别:
  • 资助金额:
    $0.11万
  • 财政年份:
    2015
  • 负责人:
    Anstett Kaitlin
  • 依托单位:
Characterization of Dolutegravir Resistance Mutation R263K by Combination with Primary INSTI Resistance Mutations
  • 批准号:
    311375
  • 项目类别:
  • 资助金额:
    $0.11万
  • 财政年份:
    2014
  • 负责人:
    Anstett Kaitlin
  • 依托单位:
Further Characterization of the Dolutegravir Resistance Mutation R263K: Combinations with Primary INSTI Resistance Mutations and Possible Compensatory Mechanisms
  • 批准号:
    311953
  • 项目类别:
    Studentship Programs
  • 资助金额:
    $1.27万
  • 财政年份:
    2013
  • 负责人:
    Anstett Kaitlin
  • 依托单位:
海外基金