Chemogenomic determination of the mechanism of action of a novel drug against multidrug resistant Burkholderia cenocepacia complex

化学基因组学测定新药抗多重耐药新洋葱伯克霍尔德菌复合体的作用机制

• 批准号: 367131
• 负责人: Hogan Andrew M
• 金额: $ 1.27万
• 依托单位: University of Manitoba
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-12-01 至 2017-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=367131&lang=en
• 关键词: Bioinformatics; Burkholderia Cenocepacia Complex; Chemogenomics; Confocal Microscopy; Cystic Fibrosis; Essential Genes; Ftsz; Gene Regulation; Next-Generation Sequencing; Novel Antibiotics

The ability of drugs to treat many deadly infectious diseases is decreasing due to emerging antibiotic resistance. Some bacteria, such as Burkholderia cenocepacia show natural resistance to many currently used antibiotics. Specifically, infection by B. ce

由于出现了抗生素耐药性，治疗许多致命传染病的药物的能力正在下降。一些细菌，如盲肠伯克霍尔德氏菌，对目前使用的许多抗生素表现出自然抗药性。具体地说，由B.ce感染