Presidential Young Investigator Award: Biopolymer Structural/Functional Relationships in Biochemical Engineering Systems

总统青年研究员奖：生化工程系统中的生物聚合物结构/功能关系

• 批准号: 8451013
• 负责人: James Rollings
• 金额: $ 31.2万
• 依托单位: Worcester Polytechnic Institute
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1985
• 资助国家: 美国
• 起止时间: 1985-06-01 至 1992-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8451013&HistoricalAwards=false
• 关键词: Presidential; Young; Investigator; Award; Biopolymer

This research deals with the study of biopolymer structure, function, and properties as they relate to biochemical engineering principles and operations. Biopolymers include proteins, polynucleic acids, and polysaccharides. The first two groups generally contain structural units with ionizable moieties and are therefore polyelectrolytes. Some polysaccharides are also polyelectrolytes, but most (cellulose, starch, and dextrans) are not charged near neutral pH. The initial phases of the directed research plan of study involves examination of these uncharged biopolymers after the "base cases" are established. Future studies will examine polyelectrolytes.

这项研究涉及生物聚合物的结构、功能和性质的研究，因为它们与生化工程原理和操作有关。生物聚合物包括蛋白质、多核酸和多糖。前两个基团通常包含具有可电离部分的结构单元，因此是聚电解质。一些多糖也是聚电解质，但大多数(纤维素、淀粉和右旋糖苷)在中性pH附近不带电。定向研究计划的初始阶段包括在“基本情况”确定后对这些不带电荷的生物聚合物进行检查。未来的研究将检验聚电解质。