Investigating the role of Signal Transducer and Activator of Transcription Factor 3 (STAT3)-mediated Astrogliosis on the Pathogenesis of Degenerative Cervical Myelopathy (DCM).

研究信号转导器和转录因子 3 激活剂 (STAT3) 介导的星形胶质细胞增生在退行性脊髓型颈椎病 (DCM) 发病机制中的作用。

• 批准号: 486252
• 负责人: Sadat Sarah
• 金额: $ 1.27万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-12-01 至 2023-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=486252&lang=en
• 关键词: Astrogliosis; Degenerative Cervical Myelopathy (Dcm); Glial Response; Immunohistochemistry (Ihc); Inflammation; Neurodegeneration; Neuroregeneration; Signal Transducer And Activator Of Transcription Factor 3; Spinal Cord Injury (Sci)

Degenerative cervical myelopathy (DCM), is the most common cause of spinal cord dysfunction amongst adults over the age of 55, involving the chronic and progressive degeneration of the cervical spinal cord. In DCM, spinal structures compress the cervical

退行性颈脊髓病（DCM）是55岁以上成人脊髓功能障碍的最常见原因，涉及慢性和进行性颈脊髓变性。在DCM中，脊柱结构压迫颈椎