MCL-1: Functions in the nucleus regulating cell cycle and DNA damage response

MCL-1：在细胞核中调节细胞周期和 DNA 损伤反应的功能

• 批准号: 201956
• 负责人: Duronio Vincent
• 金额: $ 48.51万
• 依托单位: Vancouver Coastal Health Research Institute
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-03-01 至 2015-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=201956&lang=en
• 关键词: Apoptosis; Bcl-2 Family; Cancer; Cell Division; Development; Differentiation; Dna Damage; Kinase

There are a group of proteins present in all cells that are related to the founding member of the family, Bcl-2. Depending on which of the proteins are present in any given cell, their quantity, and their level of activity, they can control whether a cell

所有细胞中都存在一组与家族创始成员Bcl-2有关的蛋白质。根据任何特定细胞中存在的蛋白质，它们的数量和活性水平，它们可以控制细胞是否