Development of a peptide-based membrane mimetic for solution studies in membrane protein research.

开发基于肽的膜模拟物，用于膜蛋白研究中的溶液研究。

• 批准号: 407901
• 负责人: Duong Franck
• 金额: $ 62.98万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-09-01 至 2024-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=407901&lang=en
• 关键词: Biochemistry; Detergent Mimetic; Membrane; Nanotechnologies; Phage Display; Protein Interactions; Protein Purification; Proteomics; Receptors; Transporters

Membrane proteins are a vital component of cells. Until recently, membrane proteins were not studied as extensively as cytosolic proteins. This is due to the propensity of membrane proteins to aggregate outside a membrane environment during their isolatio

膜蛋白是细胞的重要组成部分。直到最近，膜蛋白还没有像胞质蛋白那样被广泛研究。这是由于膜蛋白在分离过程中在膜环境外聚集的倾向。