Novel pharmacogenetic strategies to reverse autism-like phenotypes in mouse models of ASD.
在 ASD 小鼠模型中逆转自闭症样表型的新药物遗传学策略。
基本信息
- 批准号:306334
- 负责人:
- 金额:$ 66.56万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Operating Grants
- 财政年份:2014
- 资助国家:加拿大
- 起止时间:2014-03-01 至 2019-03-01
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Dysregulated translational control leads to pathological conditions like cancer, obesity, memory impairment and has been hypothesized to cause Autism Spectrum Disorders (ASD); namely through hyperconnectivity of neuronal circuits. Synaptic connections are
失调的翻译控制导致病理条件,如癌症,肥胖,记忆障碍,并已被假设为导致自闭症谱系障碍(ASD);即通过神经元回路的超连接。突触连接是
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Sonenberg Nahum其他文献
Sonenberg Nahum的其他文献
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{{ truncateString('Sonenberg Nahum', 18)}}的其他基金
Control of Host mRNA Translation in Enterovirus Infection
肠道病毒感染中宿主 mRNA 翻译的控制
- 批准号:
488671 - 财政年份:2023
- 资助金额:
$ 66.56万 - 项目类别:
Operating Grants
Regulation of long-term memory via eIF2alpha-dependent translational control mechanisms
通过 eIF2α 依赖性翻译控制机制调节长期记忆
- 批准号:
462252 - 财政年份:2022
- 资助金额:
$ 66.56万 - 项目类别:
Operating Grants
INTERCEPTORs: engINeered ThERapeutiC dEfensive Particles TO SARS-CoV-2
拦截器:针对 SARS-CoV-2 的工程治疗性防御颗粒
- 批准号:
429541 - 财政年份:2020
- 资助金额:
$ 66.56万 - 项目类别:
Operating Grants
Pharmacotherapeutic effects of cannabidiol (CBD) in autism spectrum disorder (ASD)
大麻二酚(CBD)对自闭症谱系障碍(ASD)的药物治疗作用
- 批准号:
418206 - 财政年份:2019
- 资助金额:
$ 66.56万 - 项目类别:
Operating Grants
Targeting mRNA translation to effectively treat metastatic breast cancer
靶向 mRNA 翻译有效治疗转移性乳腺癌
- 批准号:
396703 - 财政年份:2018
- 资助金额:
$ 66.56万 - 项目类别:
Operating Grants
Altered mRNA translation as a pathogenic mechanism across neurodegenerative diseases
改变 mRNA 翻译作为神经退行性疾病的致病机制
- 批准号:
374662 - 财政年份:2017
- 资助金额:
$ 66.56万 - 项目类别:
Operating Grants
Profiling eIF2a-dependent translation in synaptic plasticity and memory
分析突触可塑性和记忆中 eIF2a 依赖性翻译
- 批准号:
332309 - 财政年份:2015
- 资助金额:
$ 66.56万 - 项目类别:
Operating Grants
Translational Control of Induced Cell Reprogramming.
诱导细胞重编程的翻译控制。
- 批准号:
322999 - 财政年份:2015
- 资助金额:
$ 66.56万 - 项目类别:
Operating Grants
eIF4E-dependent translation and the mammalian circadian clock.
eIF4E 依赖性翻译和哺乳动物生物钟。
- 批准号:
323126 - 财政年份:2015
- 资助金额:
$ 66.56万 - 项目类别:
Operating Grants
Investigating mRNA translational control in the quest to cure human disease.
研究 mRNA 翻译控制以寻求治愈人类疾病。
- 批准号:
334025 - 财政年份:2015
- 资助金额:
$ 66.56万 - 项目类别:
Operating Grants
相似海外基金
PHENOCADES: Developmental neurodynamics of phenotypic cascades in autism and ADHD
现象:自闭症和多动症表型级联的发育神经动力学
- 批准号:
EP/Z000319/1 - 财政年份:2024
- 资助金额:
$ 66.56万 - 项目类别:
Research Grant
Exploring the Impact of Clinical Diagnosis on Health and Education Outcomes for Children Receiving Special Educational Needs support for Autism
探索临床诊断对接受自闭症特殊教育需求支持的儿童的健康和教育结果的影响
- 批准号:
ES/Z502431/1 - 财政年份:2024
- 资助金额:
$ 66.56万 - 项目类别:
Fellowship
The neural underpinnings of speech and nonspeech auditory processing in autism: Implications for language
自闭症患者言语和非言语听觉处理的神经基础:对语言的影响
- 批准号:
10827051 - 财政年份:2024
- 资助金额:
$ 66.56万 - 项目类别:
Elucidating the role of Cnot3 in regulating social behavior in Autism Spectrum Disorder
阐明 Cnot3 在调节自闭症谱系障碍社会行为中的作用
- 批准号:
24K18632 - 财政年份:2024
- 资助金额:
$ 66.56万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
Diagnostic and Therapeutic Potential of Circular RNAs in Autism Spectrum Disorder
环状 RNA 在自闭症谱系障碍中的诊断和治疗潜力
- 批准号:
24K10503 - 财政年份:2024
- 资助金额:
$ 66.56万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Self-recognition in children with autism spectrum disorder: Investigating of the cognitive and neural basis using MEG
自闭症谱系障碍儿童的自我认知:使用 MEG 研究认知和神经基础
- 批准号:
23K06789 - 财政年份:2023
- 资助金额:
$ 66.56万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Transforming Autism Research and Policy at the National Level: A Program for Evidence-Based Solutions and Inclusive Research
国家层面自闭症研究和政策的转变:循证解决方案和包容性研究计划
- 批准号:
487457 - 财政年份:2023
- 资助金额:
$ 66.56万 - 项目类别:
Salary Programs
Building multisectoral capacity to plan for the development and evaluation of an interactive, inclusive and patient-centered knowledge transfer tool to reduce stigma around autism
建立多部门能力,规划开发和评估交互式、包容性和以患者为中心的知识转移工具,以减少自闭症的耻辱
- 批准号:
487939 - 财政年份:2023
- 资助金额:
$ 66.56万 - 项目类别:
Miscellaneous Programs
Advancing the Autism Knowledge Synthesis Initiative: A Review of Canadian Provinces and Territories Autism Policies, Programs and Services
推进自闭症知识综合计划:加拿大各省和地区自闭症政策、计划和服务回顾
- 批准号:
484621 - 财政年份:2023
- 资助金额:
$ 66.56万 - 项目类别:
Fellowship Programs
Genetic basis of anticipation in multiplex autism families: a whole-genome sequencing study
多重自闭症家庭预期的遗传基础:全基因组测序研究
- 批准号:
23K14807 - 财政年份:2023
- 资助金额:
$ 66.56万 - 项目类别:
Grant-in-Aid for Early-Career Scientists