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Mechanisms of genome instability induced by RNA splicing defects

Mechanisms of genome instability induced by RNA splicing defects
RNA剪接缺陷导致基因组不稳定的机制
批准号:
303717
负责人:
Stirling Peter C
金额:
$46.22万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2014
资助国家:
加拿大
项目状态:
已结题
起止时间:
2014-03-01 至 2019-03-01

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中文摘要
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英文摘要
Cancer is a disease caused by mutations in normal genes. Due to so-called 'genome instability', most cancers have an increased frequency of mutations compared to normal cells. The yeast model system has proven to be a valuable tool in defining mechanisms
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Dominant genetics of cohesin pathway proteins to kill cancer
  • 批准号:
    468785
  • 项目类别:
    Operating Grants
  • 资助金额:
    $64.37万
  • 财政年份:
    2022
  • 负责人:
    Stirling Peter C
  • 依托单位:
Understanding mutagenic replication-transcription conflicts in cancer-initiation
  • 批准号:
    379690
  • 项目类别:
    Operating Grants
  • 资助金额:
    $61.58万
  • 财政年份:
    2018
  • 负责人:
    Stirling Peter C
  • 依托单位:
Understanding and exploiting RNA degradation defects in multiple myeloma
  • 批准号:
    351881
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2016
  • 负责人:
    Stirling Peter C
  • 依托单位:
Understanding and exploiting genome instability in cancer
  • 批准号:
    319938
  • 项目类别:
    Salary Programs
  • 资助金额:
    $21.86万
  • 财政年份:
    2014
  • 负责人:
    Stirling Peter C
  • 依托单位:
海外基金