Nej1 and Lif1 form structural filaments that bridge the ends of DNA at a DSB
Nej1 and Lif1 form structural filaments that bridge the ends of DNA at a DSB
批准号:
305823
负责人:
Cobb Jennifer A
金额:
$45.78万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2014
资助国家:
加拿大
项目状态:
已结题
起止时间:
2014-03-01 至 2019-03-01
中文摘要
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英文摘要
Genomic instability is a hallmark of cancer and genomic rearrangements in most cases exist before cancer is even detected. A major source of genomic instability comes from DNA damage that is not properly repaired. A double strand break (DSB) is the most
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