Acquisition of an Atomic Absorption Spectrophotometer and Furnace Atomizer

购置原子吸收分光光度计和炉原子化器

• 批准号: 8711103
• 负责人: Carol Colton
• 金额: $ 4.77万
• 依托单位: Georgetown University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-09-01 至 1991-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8711103&HistoricalAwards=false
• 关键词: Acquisition; Atomic; Absorption; Spectrophotometer; Furnace

An atomic absorption spectrophotometer with furnace atomizer is essential for ultra-micro elemental measurements in three different research projects. It will be used to determine metal content (particularly zinc and iron) in hippocampal slices. The objective is to investigate the relationship of tissue metal content to neuronal damage in the brain during exposure to oxidative stress. Another project will use this equipment to measure sodium and potassium concentrations in nanoliter samples of tubular fluid from neonatal rat kidneys. The measurements will be used to assess the role of atrial natriuretic factor in water and electrolyte homeostasis in the immature rat. For the third project, the atomic absorption spectrophotometer will also be used to determine sodium and potassium concentrations in nanoliter samples of renal tubular fluid. The role of neurohumoral factors, particularly dopamine, regulation of sodium excretion in neonatal rats will be examined. The atomic absorption spectrophotometer and graphite furnace atomizer offers the unique capability of measuring the content of various metals and ions in extremely small samples of tissue and fluid at a reasonable cost.

一种炉原子化原子吸收分光光度计， 在三个国家的超微量元素测量中必不可少 不同的研究项目。 它将被用来确定金属 含量（特别是锌和铁）。 的 目的：探讨组织金属与肿瘤的关系， 在暴露于 氧化应激 另一个项目将使用该设备， 测量纳升样品中的钠和钾浓度 新生大鼠肾脏的小管液。 测量 将用于评估心钠素在 水和电解质稳态的未成年大鼠。 为 第三个项目，原子吸收分光光度计还将 可用于测定钠和钾的浓度， 纳升的肾小管液样本 的作用 神经体液因子，特别是多巴胺，钠调节 将检查新生大鼠的排泄。 原子吸收分光光度计和石墨炉 雾化器提供了独特的能力， 各种金属和离子在非常小的组织样本， 以合理的成本提供流体。