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Memory B cells and active antibody production are present in ectopic lymphoid structures in the epicardial coronary arteries of cardiac transplant patients

Memory B cells and active antibody production are present in ectopic lymphoid structures in the epicardial coronary arteries of cardiac transplant patients
心脏移植患者心外膜冠状动脉的异位淋巴结构中存在记忆 B 细胞和活性抗体生成
批准号:
304066
负责人:
Gareau Alison
金额:
$0.08万
依托单位国家:
加拿大
项目类别:
财政年份:
2014
资助国家:
加拿大
项目状态:
已结题
起止时间:
2014-01-01 至 2014-04-01
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英文摘要
The first-line option for patients with heart failure is a transplant. Although newer drugs have improved the early survival of patients, rates of long-term survival after a transplant have not improved. This is because of a large lesion that develops in
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CNI immunosuppression does not prevent the production of donor-specific antibody capable of mediating cardiac allograft vasculopathy