Theoretical and Experimental Research into Biological Mechanisms Underlying Learning and Memory

该提案要求提供资金支持研究， 组织原则，可以解释实验 细胞水平和各种更高水平的数据。 具体目标包括： 学习突触修饰，阐明原理 控制突触的形成或修饰， 突触修饰的分子模型，构建网络 模型可以计算，学习，关联和复制这些 更高层次的认知行为，如抽象，语言习得， 和语音识别。 通过检验批判理论， 首席研究员将尝试获得更好的 了解基本的生物学机制， 中枢神经系统自我学习和组织， 精神行为的能力。 联合国主要调查人员和合作调查人员资金充足， 精通各种技术和理论 框架密切相关的研究提出。 它们非常 有资格进行这项研究。 的相互作用 理论家和实验家将允许耦合 理论和实验，这一建议的主要力量。 建议提供支持。

This proposal requests funds to support research to find principles of organization that can account for experimental data on the cellular level and on various higher levels. Specific objectives include: clarifying the dependence of learning on synaptic modification, elucidating the principles that govern synapse formation or modification, constructing a molecular model for synaptic modificaton, constructing network models that can compute, learn, associate, and reproduce such higher level cognitive acts as abstraction, language acquisition, and speech recognition. By testing critical theories, the principal investigator will attempt to obtain a better understanding of the basic biological mechanisms by which the cental nervous system learns and organizes itself and acquires its capacity for mental acts. The principal and coprincipal investigators are well funded and well versed in a wide variety of techniques and theoretical frameworks germane to the research proposed. They are well qualified to conduct the research. The interaction of theoreticians and experimentalists will allow the coupling of theory and experimentation, a major strength of this proposal. Support is recommended.