Illuminating the structure and dynamics of the proteasomal Rpn1 protein in unfolded client recognition by methyl-TROSY NMR
Illuminating the structure and dynamics of the proteasomal Rpn1 protein in unfolded client recognition by methyl-TROSY NMR
通过甲基-TROSY NMR 阐明未折叠客户识别中蛋白酶体 Rpn1 蛋白的结构和动态
批准号：
375860
负责人：
Harkness Robert
金额：
$9.83万
依托单位：
依托单位国家：
加拿大
项目类别：
Fellowship Programs
财政年份：
2017
资助国家：
加拿大
项目状态：
已结题
起止时间：
2017-11-01 至 2020-11-01
中文摘要
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英文摘要
Human health relies on the ability to properly degrade old proteins when they are no longer needed. The degradation of proteins is carried out by an enormous protein machine called the proteasome. When protein degradation is impaired, neurodegenerative di
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