Elucidating the interaction between Ail and vitronectin at the atomic level to determine the mechanism of Yersinia pestis pathogenesis.

在原子水平上阐明Ail和玻连蛋白之间的相互作用，以确定鼠疫耶尔森氏菌的发病机制。

• 批准号: 376260
• 负责人: Shin Kyungsoo
• 金额: $ 10.93万
• 依托单位: Sanford-Burnham Medical Research Institute (La Jolla, CA)
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-11-01 至 2020-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=376260&lang=en
• 关键词: Nuclear Magnetic Resonance Spectroscopy; Protein Structure Characterization; Protein-Protein Interaction; Yersinia Pestis

Yersinia pestis is the causative agent of the plague, and is responsible for the death of millions of people during massive pandemics. It is highly pathogenic as it can prevent the host's immune response and overwhelm it with massive growth. In combinatio

鼠疫耶尔森氏菌是鼠疫的病原体，在大规模流行病期间造成数百万人死亡。它是高致病性的，因为它可以阻止宿主的免疫反应，并以大量的生长压倒它。在联合