Mechanistic Organometallic Chemistry

该奖项来自无机、生物无机和有机金属化学项目，属于有机金属化学领域。 该项目的重点是新化合物的反应机制，其中两个铁原子通过烃桥连接在一起。此类化合物是合成多种有机化合物的重要试剂，有关其反应机制的信息有望促进合成方法的改进。 将探索新型二铁化合物与桥联烃配体的反应活性，并深入探讨这些化合物的新反应机理。预计这项研究将导致几种新的碳-碳键形成反应，在有机合成中具有潜在的用途。为了实现这种合成潜力，将探索从二铁配合物中裂解桥联烃基的方法。将研究金属卡宾配合物与烯烃反应中环丙烷形成的机理，并尝试在环丙化反应中生成建议的中间体，看看它们是否会生成环丙烷。将探索既不是强亲核试剂也不是强亲电试剂的金属卡宾配合物的反应，以填补金属卡宾配合物理解中的重要空白。

This award from the Inorganic, Bioinorganic and Organometallic Chemistry Program is in the area of organometallic chemistry. The focus of the project is the mechanisms of reactions of new compounds in which two iron atoms are held together by a hydrocarbon bridge. Such compounds are important reagents for the synthesis of a wide variety of organic compounds, and information about their reaction mechanisms is expected to lead to improvements in synthetic methodology. The reactivity of new diiron compounds with bridging hydrocarbon ligands will be explored, and the mechanisms of new reactions of these compounds will be explored in depth. It is anticipated that this study will lead to several new carbon-carbon bond forming reactions of potential use in organic synthesis. In order for this synthetic potential to be realized, ways of cleaving the bridging hydrocarbyl group from the diiron complex will be explored. The mechanism of cyclopropane formation in the reactions of metal-carbene complexes with alkenes will be studied, and an attempt will be made to generate the suggested intermediates in cycloproponation reactions to see if they lead to cyclopropanes. The reactions of metal carbene complexes which are neither strong nucleophiles nor strong electrophiles will be explored to fill an important gap in the understanding of metal-carbene complexes.