Mechanistic Organometallic Chemistry

机械有机金属化学

• 批准号: 8721252
• 负责人: Charles Casey
• 金额: $ 42.88万
• 依托单位: University of Wisconsin-Madison
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-03-15 至 1991-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8721252&HistoricalAwards=false
• 关键词: Mechanistic; Organometallic; Chemistry

This award from the Inorganic, Bioinorganic and Organometallic Chemistry Program is in the area of organometallic chemistry. The focus of the project is the mechanisms of reactions of new compounds in which two iron atoms are held together by a hydrocarbon bridge. Such compounds are important reagents for the synthesis of a wide variety of organic compounds, and information about their reaction mechanisms is expected to lead to improvements in synthetic methodology. The reactivity of new diiron compounds with bridging hydrocarbon ligands will be explored, and the mechanisms of new reactions of these compounds will be explored in depth. It is anticipated that this study will lead to several new carbon-carbon bond forming reactions of potential use in organic synthesis. In order for this synthetic potential to be realized, ways of cleaving the bridging hydrocarbyl group from the diiron complex will be explored. The mechanism of cyclopropane formation in the reactions of metal-carbene complexes with alkenes will be studied, and an attempt will be made to generate the suggested intermediates in cycloproponation reactions to see if they lead to cyclopropanes. The reactions of metal carbene complexes which are neither strong nucleophiles nor strong electrophiles will be explored to fill an important gap in the understanding of metal-carbene complexes.

该奖项由无机，生物无机和有机化学 化学计划是在有机金属化学领域。 该项目的重点是新的反应机制， 两个铁原子被一个铁原子结合在一起的化合物。 烃桥这些化合物是重要的试剂， 各种有机化合物的合成，以及 有关其反应机制的信息预计将导致 合成方法的改进。 新型二铁化合物的桥联反应性 烃配体将被探索，和新的机制， 将深入探讨这些化合物的反应。是 预计这项研究将导致几个新的 碳-碳键形成反应的潜在用途 有机合成为了使这种合成潜力 实现的方法是将桥连烃基从 将探索二铁络合物。的机理 金属-卡宾反应中的环丙烷生成 将研究与烯烃的络合物，并尝试 用于生成建议的中间体， 环化反应，看看它们是否会导致 环丙烷。金属卡宾络合物的反应， 既不是强亲核试剂，也不是强亲电试剂， 以填补理解的重要空白， 金属-卡宾配合物