Protection against apoptosis in presbycusis and noise/drug induced hearing loss by cochlear transfection of xiap gene in experimental animals
Protection against apoptosis in presbycusis and noise/drug induced hearing loss by cochlear transfection of xiap gene in experimental animals
批准号:
171095
负责人:
Wang Jian
金额:
$37.51万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2008
资助国家:
加拿大
项目状态:
已结题
起止时间:
2008-09-01 至 2012-09-01
中文摘要
哺乳动物耳朵中的受体细胞(毛细胞)和神经元随着年龄的增长而退化。噪音和耳毒性药物等有害因素会加剧这种退化。毛细胞的死亡主要是通过衰老等诸多因素发生的一个过程
英文摘要
The receptor cells (the hair cells) and neurons in mammalian ears degenerate with aging. This degeneration is enhanced by damaging factors such as noise and ototoxic drugs. Hair cell death due to aging and many other factors occurs mainly through a proces
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会议论文
Canada Research Chair Tier 1
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批准号:453805
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项目类别:
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资助金额:$101.99万
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财政年份:2020
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负责人:Wang Jian
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依托单位:
Factuality and Mechanisms of Promoting Effect of Hearing Loss on Age-related Cognitive Impairment
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批准号:366619
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项目类别:Operating Grants
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资助金额:$7.29万
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财政年份:2016
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负责人:Wang Jian
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依托单位:
Cochlear gene therapy targeting the protection against aging related hearing loss and neuronal degeneration
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批准号:304476
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项目类别:Operating Grants
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资助金额:$18.25万
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财政年份:2014
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负责人:Wang Jian
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依托单位: