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Vitamin D agonists/histone deacetylase inhibitor hybrids as potential therapeutics.

Vitamin D agonists/histone deacetylase inhibitor hybrids as potential therapeutics.
维生素 D 激动剂/组蛋白脱乙酰酶抑制剂混合物作为潜在的治疗方法。
批准号:
172278
负责人:
White John H
金额:
$25.7万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2008
资助国家:
加拿大
项目状态:
已结题
起止时间:
2008-09-01 至 2011-09-01

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中文摘要
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英文摘要
The hormonal form of vitamin D, 1,25-dihydroxyvitamin D3 (1,25D) binds to the vitamin D receptor (VDR) and is a key regulator of calcium homeostasis. However, data from multiple sources, including one of the applicants (White), showed that 1,25D is a pote
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Vitamin D signaling in the thymic microenvironment and its functional cooperation with Aire.
  • 批准号:
    450584
  • 项目类别:
    Operating Grants
  • 资助金额:
    $66.32万
  • 财政年份:
    2021
  • 负责人:
    White John H
  • 依托单位:
Consequences of ultraviolet light-induced aryl hydrocarbon receptor signaling on intestinal immunity
  • 批准号:
    355925
  • 项目类别:
    Operating Grants
  • 资助金额:
    $64.37万
  • 财政年份:
    2016
  • 负责人:
    White John H
  • 依托单位:
FBW7-dependent regulation of cMYC and MXD1 function by the vitamin D receptor
  • 批准号:
    279017
  • 项目类别:
    Operating Grants
  • 资助金额:
    $27.7万
  • 财政年份:
    2013
  • 负责人:
    White John H
  • 依托单位:
Regulation of FoxO protein and cMYC function by the vitamin D receptor
  • 批准号:
    249032
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2011
  • 负责人:
    White John H
  • 依托单位:
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