Dissecting Signaling Pathways Regulating Internal Ribosome Entry Site-mediated Translation

剖析调节内部核糖体进入位点介导翻译的信号通路

• 批准号: 184668
• 负责人: Jordan Lindsay E
• 金额: $ 7.65万
• 依托单位: Children's Hospital of Eastern Ontario Research Institute Inc
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-10-01 至 2011-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=184668&lang=en
• 关键词: Apoptosis; Bcl-Xl; Cancer; Ires; Pdcd4; Rna Binding Proteins; S6 Kinase 2; Translation; Translational Control; Xiap

Programmed cell death, or apoptosis, is crucial in protecting against human disease, particularly in cells that have incurred DNA damage or have pathogenic properties. XIAP and Bcl-xL are members of the two classes of proteins that control apoptosis. The

程序性细胞死亡或细胞凋亡在预防人类疾病方面至关重要，特别是在已经发生DNA损伤或具有致病性的细胞中。XIAP和Bcl-xL是控制细胞凋亡的两类蛋白质的成员。的