Role of the Amygdala-Prefrontal Cortical Circuit in Opiate Motivation, Learning and Memory

杏仁核-前额皮质回路在阿片类药物动机、学习和记忆中的作用

• 批准号: 252872
• 负责人: Laviolette Steven R
• 金额: $ 41万
• 依托单位: University of Western Ontario
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-03-01 至 2017-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=252872&lang=en
• 关键词: Addiction; Amygdala; Dopamine; In Vivo Electrophysiology; Memory; Mesolimbic System; Neuronal Recording; Opiates; Prefrontal Cortex

Opiate-class narcotics such as heroin and morphine represent highly addictive drugs of abuse, capable of inducing rapid dependence and withdrawal. Indeed, addiction to opiates, either illicit or prescription based, represents a rapidly growing public heal

鸦片类麻醉品，如海洛因和吗啡，是高度成瘾的滥用药物，能够引起迅速的依赖和戒断。事实上，阿片类药物成瘾，无论是非法的还是基于处方的，都是一种迅速增长的公共疗法。