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Developing Preclinical Optical Imaging Tools for Studying Vasculature, Microenvironment, and Radiation Response of Solid Tumours In Vivo.

Developing Preclinical Optical Imaging Tools for Studying Vasculature, Microenvironment, and Radiation Response of Solid Tumours In Vivo.
开发用于研究体内实体瘤的脉管系统、微环境和辐射响应的临床前光学成像工具。
批准号：
252652
负责人：
Dacosta Ralph S
金额：
$32.62万
依托单位：
University Health Network (Toronto)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2012
资助国家：
加拿大
项目状态：
已结题
起止时间：
2012-03-01 至 2016-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=252652&lang=en
关键词：
Genomic And Proteomic Profiling Hypoxia And Oxygenation Intravital Optical Molecular Imaging Phosphorescence Lifetime Imaging Photoacoustic Microscopic Imaging Radiation Response Spatio-Temporal Dynamics Tumor Cell Death And Vascular Damage Xenogr

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中文摘要
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英文摘要
Tumor vasculature and hypoxia (a lack of oxygen, O2) greatly influence tumor response to RT and both are attractive targets for improving response to therapy (e.g. new hypoxia-activated drugs are in clinical testing with RT to improve treatment outcome).
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