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PI3K gamma is required for linkage between VLA-4 integrins and the actin cytoskeleton, a critical step for leukocyte recruitment from blood to extravascular tissues

PI3K gamma is required for linkage between VLA-4 integrins and the actin cytoskeleton, a critical step for leukocyte recruitment from blood to extravascular tissues
PI3K gamma 是 VLA-4 整合素和肌动蛋白细胞骨架之间的连接所必需的,这是白细胞从血液募集到血管外组织的关键步骤
批准号:
184382
负责人:
Rullo Jacob
金额:
$1.7万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2008
资助国家:
加拿大
项目状态:
已结题
起止时间:
2008-10-01 至 2009-06-01

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英文摘要
The recruitment of white blood cells (leukocytes) from the blood into tissues is an important process. Leukocyte recruitment is central to the development of many inflammatory diseases including multiple sclerosis, transplant/organ rejection and atherosc
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