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Determining commonly modulated gene targets and cellular pathways in Acute Promyelocytic Leukemia.

Determining commonly modulated gene targets and cellular pathways in Acute Promyelocytic Leukemia.
确定急性早幼粒细胞白血病中常见调节的基因靶标和细胞途径。
批准号:
184343
负责人:
Thomas Mariam
金额:
$7.65万
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2008
资助国家:
加拿大
项目状态:
已结题
起止时间:
2008-10-01 至 2011-10-01

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中文摘要
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英文摘要
Acute Promyelocytic Leukemia (APL) results in production of abnormal white blood cells, and arises from specific acquired gene rearrangements in cells of the bone marrow. These gene rearrangements give rise to abnormal proteins ("X-RARalpha") which in tur
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