Glycosyltransferases and their role in protein folding and quality control

糖基转移酶及其在蛋白质折叠和质量控制中的作用

• 批准号: 266061
• 负责人: Rini James M
• 金额: $ 67.96万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-09-01 至 2017-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=266061&lang=en
• 关键词: Glycosyltransferases; Pofut1; Pofut2; Protein Folding; Protein-O-Fucosyltransferase; Udp-Glc:Glycoprotein Glucosyltransferase; Uggt

Glycosyltransferases are enzymes that add monosaccharides to either proteins or carbohydrates. In the ER of eukaryotic cells there are glycosyltransferases that are involved in ensuring that proteins destined for the cell surface or for secretion are pro

糖基转移酶是将单糖添加到蛋白质或碳水化合物中的酶。 在真核细胞的内质网中，存在糖基转移酶，其参与确保预定用于细胞表面或分泌的蛋白质在内质网中表达。