Mechanisms of Reaction of Organometallic Radicals and Insertion Reactions

有机金属自由基和插入反应的反应机理

• 批准号: 8815958
• 负责人: William Trogler
• 金额: $ 50.9万
• 依托单位: University of California-San Diego
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-01-01 至 1993-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8815958&HistoricalAwards=false
• 关键词: Mechanisms; Reaction; Organometallic; Radicals; Insertion

William C. Trogler of the University of California at San Diego will study the synthesis, structure and reaction mechanisms of 17-electron organometallic radicals as part of this project within the Inorganic, Bioinorganic and Organometallic Chemistry Program. The goal is to develop catalysts for new chemical transformations that could be applied to the synthesis of specialty chemicals and medicinal compounds. Another thrust of the project is the investigation of late transition metal coordination complexes as possible reagents for the activation of nitrogen-hydrogen and oxygen-hydrogen bonds in order to facilitate insertion of unsaturated organic compounds such as olefins into the metal-nitrogen and metal-oxygen bonds, respectively. This area is also aimed at better defining the requirements for catalytic addition of ammonia, amines and alcohols to carbon-carbon double bonds. Compounds to be employed in the first part of the project are neutral electron rich 18-electron complexes which can be electrochemically oxidized to give stable or short-lived cationic radicals. Representative of these are dicarbonyl(olefin)cyclobutadieneiron, (tertiary- phosphine)(olefin)cyclopentadienylcobalt and bis(olefin)cyclopentadienylrhodium. Compounds employed in the second part of the study will be mainly from the platinum group of metals.

William C.位于圣地亚哥的加州大学的特罗格勒 将研究的合成，结构和反应机理 17-电子有机金属自由基作为这个项目的一部分 在无机，生物无机和有机化学 程序.目标是开发新化学品的催化剂 可以应用于合成的转换 特种化学品和药用化合物。另一个推力 该项目是研究后过渡金属 配位络合物作为活化的可能试剂 氮-氢键和氧-氢键的结合 促进不饱和有机化合物的插入， 烯烃转化为金属-氮和金属-氧键， 分别这一领域还旨在更好地界定 氨、胺和氨的催化加成要求 碳-碳双键。 项目第一部分使用的化合物 是中性富电子18电子络合物， 电化学氧化以产生稳定或短寿命的 阳离子自由基其中有代表性的是 二羰基（烯烃）环丁二烯铁，（叔- 膦）（烯烃）环己烯基钴和 双（烯烃）环戊二烯基铑。中采用的化合物 研究的第二部分将主要来自铂组 金属。