Role of Ankyrin3, an ubiquitin adapter protein, in platelet-derived growth factor receptor degradation

泛素接头蛋白 Ankyrin3 在血小板衍生生长因子受体降解中的作用

• 批准号: 188440
• 负责人: Furber Levi A
• 金额: $ 2.4万
• 依托单位: University of Saskatchewan
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-10-01 至 2011-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=188440&lang=en
• 关键词: Adenovirus; Ankyrin3; Breast Cancer; Cell Culture; Endocytosis; Endosomal Trafficking; Metabolic Labeling; Phosphoinositol-3 Kinase Signaling; Receptor Tyrosine Kinase Degradation; Ubiquitination

Excessive receptor signaling leads to uncontrolled cell division and cancer development. A variety of receptors are displayed on the surfaces of most cells in the body. Generally, these receptors function to detect changes in the outside environment and s

过度的受体信号传导导致不受控制的细胞分裂和癌症发展。多种受体显示在体内大多数细胞的表面上。一般来说，这些受体的功能是检测外界环境的变化，