课题基金 / 基金详情

RUI: Hormonal and Behavioral Attachment Responses

RUI: Hormonal and Behavioral Attachment Responses
RUI:荷尔蒙和行为依恋反应
批准号:
8822240
负责人:
Michael Hennessy
金额:
$11.4万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
1989
资助国家:
美国
项目状态:
已结题
起止时间:
1989-08-15 至 1992-01-31

项目摘要

项目成果

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中文摘要
翻译
非自愿与母亲分离的婴儿可能会 遭受严重的生理和行为后果。 大部分 我们所知道的生理效应 从非人类灵长类动物的研究中 这些影响包括 交感神经活动增加,神经递质变化 水平,并增加垂体肾上腺系统的活动, 与压力有关的神经内分泌系统。 多年来, 只有在灵长类动物身上才有可能研究这些问题, 普通实验室啮齿动物被认为对 分离的方式与灵长类动物完全不同, 可能是人类 在他之前的NSF支持下,Hennessy博士 证明了年轻豚鼠对母亲的反应, 分离在很多方面与灵长类相似。 的 豚鼠模型为灵长类动物研究提供了另一种选择 这又提供了许多实际的优点。 轩尼诗博士 将继续他的研究,以进一步了解如何 短暂的母亲分离会改变神经内分泌和 行为功能 这些研究将有助于我们 了解母婴分离的后果, 附着过程,并阐明应力的性质 年轻人的回答
英文摘要
Infants that are involuntarily separated from their mothers may suffer severe physiological and behavioral consequences. Most of what we know concerning the physiological effects has derived from studies using nonhuman primates. These effects include increases in sympathetic activity, changes in neurotransmitter levels, and increased activity of the pituitary-adrenal system, a neuroendocrine system associated with stress. For many years, it was only possible to study such questions in primates since common laboratory rodents have been thought to respond to separation in a fundamentally different way than do primates, and possibly humans. With his previous NSF support, Dr. Hennessy demonstrated that the responses of young guinea pigs to maternal separation are in many ways similar to those of primates. The guinea pig model provides an alternative to primate research which, in turn, offers many practical advantages. Dr. Hennessy would continue his research to further our understanding of how brief periods of maternal separation alter neuroendocrine and behavioral functioning. These studies will contribute to our understanding of the consequences of mother-infant separation and processes of attachment and elucidate the nature of the stress response in young.
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Mechanisms of Social Buffering of Hypothalamic-Pituitary-Adrenal Responses
  • 批准号:
    1120932
  • 项目类别:
    Standard Grant
  • 资助金额:
    $33.0万
  • 财政年份:
    2011
  • 负责人:
    Michael Hennessy
  • 依托单位:
Endocrine Activity and the Ontogeny of Social Interactions and Bonding
  • 批准号:
    0514509
  • 项目类别:
    Standard Grant
  • 资助金额:
    $30.1万
  • 财政年份:
    2005
  • 负责人:
    Michael Hennessy
  • 依托单位:
Social Influences on Endocrine and Behavioral Responses During Development
  • 批准号:
    0080320
  • 项目类别:
    Standard Grant
  • 资助金额:
    $26.78万
  • 财政年份:
    2000
  • 负责人:
    Michael Hennessy
  • 依托单位:
Maternal Influences on Hormonal Activity and Behavior
  • 批准号:
    9729595
  • 项目类别:
    Standard Grant
  • 资助金额:
    $13.01万
  • 财政年份:
    1998
  • 负责人:
    Michael Hennessy
  • 依托单位:
海外基金