Characterization of the conformation preferentially sampled by the envelope glycoproteins of transmitted/founder HIV-1 viruses

传播/创始人 HIV-1 病毒的包膜糖蛋白优先采样的构象特征

• 批准号: 283871
• 负责人: Veillette Maxime
• 金额: $ 7.65万
• 依托单位: Centre hospitalier de l'Universit de Montral (CHUM)
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-10-01 至 2015-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=283871&lang=en
• 关键词: Env Gps Conformational Changes; Gp120-Gp41 Interactions; Hiv; Isothermal Calorimetry; Surface Plasmon Resonance; Transmitted/Founder Virus; Viral Replication

The first cases of infection with human immunodeficiency virus (HIV) in Canada were reported over 25 years ago. Notwithstanding all the efforts to prevent new infections, it is estimated that 65,000 Canadians are living with HIV/AIDS and thousands are new

25 年前，加拿大报告了第一例人类免疫缺陷病毒 (HIV) 感染病例。尽管采取了一切努力来预防新感染，但估计仍有 65,000 名加拿大人感染艾滋病毒/艾滋病，其中数千人是新感染者