Equipment for an Undergraduate Biotechnology Laboratory Program

将为生物化学项目建立综合生物技术和计算机实验室，培训生物学、生物化学、化学和其他专业的学生学习重组DNA和单克隆抗体的生产和规模化方法。因为这些方法已经成为许多科学领域的基础，所以大学生应该培养这些技能，以便在必要的实习和自己的研究中使用。在过去的七年中，本系生物化学专业的学生人数稳步增加；80%的人会去读医学院或研究生院。DNA电泳和印迹设备，倒置显微镜，超冷冷冻室，制备离心机，发酵罐和两个分光光度计允许DNA限制定位，克隆，和生产蛋白质和单克隆抗体。正在建立一个生物计算中心，在那里教师开发的软件可以让学生获得实验设计，数据收集和分析的经验，除了他们的实验室经验。这个项目的两个创新特点是：1)将动手实验与计算机模拟相结合，允许在短时间内以低成本获得实际的实验设计和数据分析的实验室经验；2)实验室为学生准备实习和研究的方式，在实习和研究中，人们合作进行整合多种方法的长期项目。受资助机构将从非联邦来源获得等额的NSF奖励。

Integrated biotechnology and computer labs for the Biochemistry program will be set up to train biology, biochemistry, chemistry and other majors in recombinant DNA and monoclonal antibody production and scale-up methods. Because these methods have become basic to many areas of science, should develop these skills as undergraduates for use in required internships and their own research. The number of biochemistry majors in this department has steadily increased over the past seven years; 80% of them going on to medical or graduate schools. DNA electrophoresis and blotting equipment, an inverted microscope, an ultracold freezer, a preparative centrifuge, a fermenter and two spectrophotometers permit DNA restriction mapping, cloning, and the production of proteins and monoclonal antibodies. A Biology Computing Center is being established where faculty developed software allows students to gain experience with experimental design, data collection and analysis, in addition to their lab experience. Two innovative features of this project are 1) the integration of the hands-on labs with computer simulations, allowing for practical lab experience with realistic experimental design and data analysis in a short period at low cost, and 2) the way in which labs prepare students for internships and research where people cooperate on long- term projects that integrate several methods. The grantee institution is matching the NSF award with an equal sum obtained from non-Federal sources.