Development of a mutant human coagulation protein as a novel antidote for new direct factor Xa anticoagulant drugs, and as a tool for investigating the activity and regulation of intrinsic and extrinsic tenase, key enzyme complexes in blood coagulation.
Development of a mutant human coagulation protein as a novel antidote for new direct factor Xa anticoagulant drugs, and as a tool for investigating the activity and regulation of intrinsic and extrinsic tenase, key enzyme complexes in blood coagulation.
开发突变型人类凝血蛋白，作为新型直接 Xa 因子抗凝血药物的新型解毒剂，并作为研究凝血中关键酶复合物内在和外在 Tenase 的活性和调节的工具。
批准号：
278235
负责人：
Yeh Calvin H
金额：
$0.04万
依托单位：
依托单位国家：
加拿大
项目类别：
财政年份：
2013
资助国家：
加拿大
项目状态：
已结题
起止时间：
2013-01-01 至 2013-04-01
中文摘要
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英文摘要
Heart attacks and strokes, the number one cause of death and disability in Canada, are often caused by defective blood clotting in the human body. This research project aims to translate discoveries made on the scientific bench to the bedside by figuring
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The BEACONS Platform - Comprehensive biomarker analysis for prediction of clinical course and management in acute coagulopathy in sepsis, trauma, cardiac arrest, and COVID-19
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批准号：454967
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项目类别：Fellowship Programs
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资助金额：$12.02万
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财政年份：2021
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负责人：Yeh Calvin H
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依托单位：
Design of a novel mutant human coagulation protein as a new anticoagulant drug, and as a tool for investigating the activity and regulation key enzymes in blood coagulation.
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批准号：283889
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项目类别：Studentship Programs
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资助金额：$7.65万
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财政年份：2012
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负责人：Yeh Calvin H
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依托单位：
FIXa protection from heparin-antithrombin inhibition when incorporated into the intrisic tenase complex
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批准号：199647
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项目类别：Studentship Programs
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资助金额：$1.27万
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财政年份：2010
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负责人：Yeh Calvin H
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依托单位：
海外基金
