Sub-cellular regulation of Zinc homeostasis and mobilization in T cells and its role in cell activation.

T 细胞中锌稳态和动员的亚细胞调节及其在细胞激活中的作用。

• 批准号: 293476
• 负责人: Gagnon Etienne
• 金额: $ 49.51万
• 依托单位: Institute for Research in Immunology and Cancer (Montreal, QC)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-09-01 至 2018-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=293476&lang=en
• 关键词: Fret; Immunological Synapse; Intra-Cellular Signaling; T Cells; Zinc Hoemeostasis

The intrinsic ability of the immune system to discriminate between self and non-self is crucial in the prevention or elimination of infection and disease. Our capacity to recognize disease-causing foreign invaders is dependent on the innate immune respons

免疫系统区分自我和非自我的内在能力对于预防或消除感染和疾病至关重要。我们识别致病外来入侵者的能力依赖于先天免疫反应。