RUI: Acquisition of an Ultramicratome and Acillaries for Research in the Department of Biology

目前正在提交一份收购超微显微镜、防震台和刀机的提案。共提交了四个建议项目。项目一将研究龙（蜥蜴）精子的精细结构及其发育。它的主要目的是阐明蜥蜴精子的中心区（头部和尾部之间）的精细结构，并描述美国南部蜥属石龙子精子发生的过程。项目二旨在阐明促性腺激素（LH）与小鼠附睾在超微结构水平上激素受体结合的细节。目前在光镜水平上获得的结果表明，小鼠附睾中LH受体的浓度可能在高尔基复合体和内质网中。结合的实际位置可以用电镜免疫组织化学确定。项目三将研究子囊菌科（Clavipitaceae）真菌内生菌与其草宿主之间的真菌-宿主相互作用，目的是揭示真菌和宿主细胞的精细结构变化，使这两种生物能够相互生存。第四个项目将检查一些分离的嗜睡嗜血杆菌，这种细菌是血栓栓塞性脑膜脑炎和某些类型的牛生殖衰竭的病原体，是否可能存在一种胶囊，目的是发现它附着在宿主细胞上的方法。

A proposal is being submitted to acquire an ultramicrotome, an anti-vibration table and a knife-maker. There are four proposed projects submitted. Project one will study the fine structure of the skink (lizard) spermatozoan and its development. Its principle aim will be to elucidate the fine structure of the centriolar region (between head and tail) of the lizard sperm and to describe the process of spermatogenesis in the southern united states skinks of the genus Eumeces. Project two is aimed at elucidating the details of hormone-receptor binding between gonadotrophins (LH) and the mouse epididymis at the ultrastructural level. Results so far obtained at the light microscope level indicate a possible concentration of receptors for LH in the mouse epididymis perhaps in the Golgi complex and endoplasmic reticulum. The actual site of binding may be determined using electron microscope immunohistochemistry. Project three will study fungus-host interactions between fungal endophytes of the family Clavipitaceae (Ascomycotina) and their grass hosts with the objective of unraveling the fine structural changes of fungal and host cells that permit the two organisms to exist mutualistically. The fourth project will examine several isolates of Haemophilus somnus, a bacterium that is the causative agent of thromboembolic meningoencephalitis and certain types of reproductive failure in cattle, for possible presence of a capsule, with the objective of discovering its method of adherence to host cells.