A Central Shared Computer Resource for Molecular and Cellular Biology

本提案的目的是筹集资金， VAX 6210计算机将取代目前 作为医疗系统内的中央计算机资源， 中心 这台中央计算机提供数据库存储， 计算能力，几乎所有的研究科学家在医疗 其工作涉及分子生物学。 的任何项目 专注于DNA或蛋白质序列的测定， 试图将这些序列与其他人获得的序列联系起来， 实验室需要访问包含此信息的数据库 信息，以及快速可靠地利用它的程序。 共享资源的目标是增强当前的服务 并提供新设施，其中一些正在发展中， 医学中心 这些资源包括新的数据库、工具 用于可视化分子结构和图像 使用文件和计算服务技术的处理工具。 因此，研究人员将能够探索生物学 从分子到细胞的各个层次的结构， 目前在医疗中心没有机会。 的 PI和Co-PI目前，并预计将继续 计算机系统的主要用户。 它们共享一个 共享计算资源的承诺，并参与 项目，这将提高其价值的医疗中心 社区

The purpose of this proposal is to generate funds to purchase a VAX 6210 computer to replace the VAX 750 which currently functions as a central computer resource within the Medical Center. This central computer provides databank storage and computing power for nearly all research scientists in the Medical Center whose work involves molecular biology. Any project that focuses on the determination of DNA or protein sequences and seeks to relate those sequences to ones obtained by other laboratories needs to have access to a data bank containing this information, and the programs to rapidly and reliably exploit it. The goal of the shared resource is to enhance current services and to provide new facilities, some under development in the Medical Center. These resources consist in new databases, tools for the visualization of molecular structure, and image processing tools employing file and compute service technologies. Investigators will therefore be able to explore biological structure at all levels from the molecular to the cellular, an opportunity not available at present at the Medical Center. The PI and the Co-PIs are currently, and expect to continue to be major users of the computer system in the future. They share a commitment to a shared computing resource and are involved in projects which will enhance its value to the Medical Center community.