Determination of Structure-Function Redox Potential Relationships for Flavoproteins and Metalloenzymes

黄素蛋白和金属酶的结构-功能氧化还原电位关系的测定

• 批准号: 8908414
• 负责人: Marian Stankovich
• 金额: $ 5.34万
• 依托单位: University of Minnesota-Twin Cities
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-09-01 至 1992-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8908414&HistoricalAwards=false
• 关键词: Determination; Structure; Function; Redox; Potential

This Research Opportunities for Women Career Advancement Award project is in the general area of analytical and surface chemistry and in the subfield of bioelectrochemistry. During the twelve month period beginning 1 September 1989, Professor Stankovich will undertake a program to develop expertise in genetic engineering such that she can produce metalloenzymes with well-defined molecular characteristics to serve as models with which she can test theories of biological electron transfer processes. To acquire this expertise, Professor Stankovich will collaborate with Professor Grant Mauk of the University of British Columbia who is an expert in the area of site directed mutagenesis. This Career Advancement Award will enable Professor Stankovich to broaden significantly her research capabilities in the area of bioelectrochemistry. The results of this research could bear significantly on the current understanding of biological electron transfer processes.

该女性职业发展研究机会奖项目属于分析和表面化学的一般领域以及生物电化学的子领域。 从1989年9月1日开始的十二个月期间，斯坦科维奇教授将开展一项发展基因工程专业知识的计划，以便她能够生产具有明确分子特征的金属酶，作为她可以测试生物电子转移过程理论的模型。 为了获得这一专业知识，斯坦科维奇教授将与不列颠哥伦比亚大学的格兰特·莫克教授合作，他是定点诱变领域的专家。 该职业进步奖将使斯坦科维奇教授能够显着扩大她在生物电化学领域的研究能力。 这项研究的结果可能对当前对生物电子转移过程的理解产生重大影响。