Novel Properties of Side Population Cells in Mesenchymal Neoplasia and How to Effectively Target Them

间质瘤中侧群细胞的新特性以及如何有效靶向它们

• 批准号: 182309
• 负责人: Wang Chang Ye (Yale)
• 金额: $ 1.27万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-02-01 至 2010-02-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=182309&lang=en
• 关键词: Cellular Quiesence; Chemo-Resistance; Chemotherapy; Sarcoma; Stem-Cells

Cancer stem cells (CSCs) have been identified in a variety of solid cancers, such as those in lung, breast, pancreatic, and colon. Experimentally, CSC possesses stem-like quality in its ability to self-renew, as well as to differentiate into other tumor c

癌症干细胞（CSC）已经在多种实体癌中被鉴定，例如在肺癌、乳腺癌、胰腺癌和结肠癌中。在实验中，CSC具有干细胞样的自我更新能力，以及分化为其他肿瘤细胞的能力。