Studies in Molecular Recognition

斯蒂尔的研究得到了合成有机计划的支持。 斯蒂尔是哥伦比亚大学的化学教授， 研究如何准备和计算机模型结构， 复杂有机分子的反应。 他的工作已经 影响了化学家如何设计和分析分子 结构，他的研究继续引领这一方向 非常重要的领域。 该项目的目标是：1）编写一系列 构象受限的主体分子，具有三个- 三维结合位点，2）研究它们的几何形状， 与客体分子的结合特性，以及3）使用数据 获得测试和评估计算方法， 预测结合性能。

Still's research is supported by the Synthetic Organic Program. A professor of Chemistry at Columbia University, Still is studying how to prepare and computer-model structures and reactions of complex organic molecules. His work has already had impact on how chemists design and analyze molecular structure, and his studies continue to lead the way in this very important area. The objectives of this project are: 1) to prepare a series of conformationally restricted host molecules with three- dimensional binding sites, 2) to study their geometries and binding properties with guest molecules, and 3) to use the data obtained to test and evaluate a computational method for predicting binding properties.