A high-resolution view of death in bacteria: Providing new insight into antimicrobial efficacy and bacterial programmed cell death using cryogenic electron tomography

细菌死亡的高分辨率视图：使用低温电子断层扫描提供抗菌功效和细菌程序性细胞死亡的新见解

• 批准号: 318935
• 负责人: Baker Lindsay
• 金额: $ 7.29万
• 依托单位: University of Oxford (England)
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-11-01 至 2016-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=318935&lang=en
• 关键词: Antibiotics; Bacterial Programmed Cell Death; Correlative Light And Electron Microscopy; Electron Tomography

Bacteria are an important cause of human disease. The discovery of antibiotics changed medicine, as surgeries could be completed without severe infections. Unfortunately, bacteria are constantly evolving ways to avoid the lethal effects of antibiotics, an

细菌是人类疾病的重要原因。抗生素的发现改变了医学，因为手术可以在没有严重感染的情况下完成。不幸的是，细菌不断进化以避免抗生素的致命作用，