Improvement of cell plasma membrane research capabilities in biology

提高生物学细胞质膜研究能力

• 批准号: 8912685
• 负责人: A. James Hicks
• 金额: $ 30万
• 依托单位: North Carolina Agricultural & Technical State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-10-01 至 1993-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8912685&HistoricalAwards=false
• 关键词: Improvement; cell; plasma; membrane; research

This Research Improvement in Minority Institutions (RIMI) project will use novel biological techniques to improve the institution's cell plasma membrane research capabilities. These studies will focus on the effects of genetics, developmental and environmental influences on plasma membrane properties for freshwater mussel and the aquatic bacterium Caulobacter crescentus. It is expected that plasma membrane fluidity, composition and binding properties will change in response to environmental and developmental signals. Chromatography and fluorescence polarization will be used to monitor these changes. This comprehensive study involving comparative physiology and physiological ecology will significantly increase the research capability of a predominantly minority institution The principal investigators have the necessary training background and experience to do the research. Faculty and students working on this project will have opportunities to use new procedures to investigate the role of lipid membrane fluidity in the function and development of certain cells.

少数民族机构研究改进（RIMI） 该项目将使用新的生物技术来改善 研究机构的细胞质膜研究能力。 这些研究将集中在遗传学的影响， 发育和环境对质膜的影响 淡水贻贝和水生细菌的特性 新月柄杆菌 预计质膜 流动性、组成和粘合性能将发生变化， 对环境和发展信号的反应。 将使用层析和荧光偏振来 监测这些变化。 这项涉及比较生理学和 生理生态学将大大增加研究 一个占主导地位的少数民族机构的能力 主要研究者具有必要的培训背景 and experience经验to do the research研究. 教师和学生 在这个项目上工作将有机会使用新的 研究脂膜流动性作用的方法 在某些细胞的功能和发育中。