Cation Radical Explorations

有机动力学计划的这笔赠款支持 约瑟夫·P·迪诺森佐博士在大学的持续工作 他正在研究分子的反应， 其中一个电子被移除。 调查 这些活性物质将提供基本信息， 酸碱反应，并应导致新的方法， 合成有机化学 迪诺森佐博士的实验 包括阳离子自由基的两个相关研究。 第一个目的是提供一个详细的了解 叔胺阳离子自由基的动力学酸度， 烷基芳族阳离子自由基。 制备、表征、 可分离阳离子自由基盐的质子转移研究 将提供动力学和热力学数据， 确定阳离子之间的异同 自由基去质子化和中性闭壳层的去质子化 有机分子 第二项调查旨在 阐明的范围，机制，和合成应用 具有不饱和环丙烷的阳离子自由基反应 取代基。

This grant from the Organic Dynamics Program supports the continuing work of Dr. Joseph P. Dinnocenzo at the University of Rochester, who is studying the reactions of molecules from which a single electron has been removed. Investigations of these reactive species will provide fundamental information on acid-base reactions and should lead to new methodology in synthetic organic chemistry. The experiments to be carried out by Dr. Dinnocenzo will comprise two related investigations of cation radicals. The first is designed to provide a detailed understanding of the kinetic acidities of tertiary amine cation radicals and alkylaromatic cation radicals. Preparation, characterization, and proton-transfer studies of isolable cation radical salts will afford kinetic and thermodynamic data that will help to identify the similarities and differences between cation radical deprotonations and those of neutral, closed-shell organic molecules. The second investigation is designed to elucidate the scope, mechanism, and synthetic applications of cation radical reactions for cyclopropanes having unsaturated substituents.