Cation Radical Explorations

阳离子自由基探索

• 批准号: 8918556
• 负责人: Joseph Dinnocenzo
• 金额: $ 23.85万
• 依托单位: University of Rochester
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-02-01 至 1993-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8918556&HistoricalAwards=false
• 关键词: Cation; Radical; Explorations

This grant from the Organic Dynamics Program supports the continuing work of Dr. Joseph P. Dinnocenzo at the University of Rochester, who is studying the reactions of molecules from which a single electron has been removed. Investigations of these reactive species will provide fundamental information on acid-base reactions and should lead to new methodology in synthetic organic chemistry. The experiments to be carried out by Dr. Dinnocenzo will comprise two related investigations of cation radicals. The first is designed to provide a detailed understanding of the kinetic acidities of tertiary amine cation radicals and alkylaromatic cation radicals. Preparation, characterization, and proton-transfer studies of isolable cation radical salts will afford kinetic and thermodynamic data that will help to identify the similarities and differences between cation radical deprotonations and those of neutral, closed-shell organic molecules. The second investigation is designed to elucidate the scope, mechanism, and synthetic applications of cation radical reactions for cyclopropanes having unsaturated substituents.

有机动力学计划的这笔资助支持罗切斯特大学 Joseph P. Dinnocenzo 博士的持续工作，他正在研究被去除单个电子的分子的反应。 对这些活性物质的研究将提供酸碱反应的基本信息，并应导致合成有机化学的新方法。 Dinnocenzo 博士将进行的实验将包括两项有关阳离子自由基的相关研究。 第一个旨在提供对叔胺阳离子自由基和烷基芳族阳离子自由基的动力学酸度的详细理解。 可分离阳离子自由基盐的制备、表征和质子转移研究将提供动力学和热力学数据，有助于识别阳离子自由基去质子化与中性闭壳有机分子去质子化之间的异同。 第二项研究旨在阐明具有不饱和取代基的环丙烷的阳离子自由基反应的范围、机理和合成应用。