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Effect of environmental contaminants and methylome of breast adipose tissue on aromatase inhibitor efficacy in breast cancer

Effect of environmental contaminants and methylome of breast adipose tissue on aromatase inhibitor efficacy in breast cancer
环境污染物和乳腺脂肪组织甲基化对乳腺癌芳香酶抑制剂疗效的影响
批准号：
344407
负责人：
Diorio Caroline
金额：
$37.31万
依托单位：
Universit Laval
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2016
资助国家：
加拿大
项目状态：
已结题
起止时间：
2016-03-01 至 2020-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=344407&lang=en
关键词：
Adipose Tissue Aromatase Inhibitors Breast Cancer Environmental Contaminants Estrogen Mass Spectometry Methylation Treatment

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中文摘要
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英文摘要
Aromatase inhibitors (AIs) are considered gold-standard therapy against hormone-dependent breast tumors which make up 80% of all breast cancers (BC). This treatment significantly reduces the risk of BC recurrence and mortality. However, about 10-15% wome
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Targeting CD38 in T-cell acute lymphoblastic leukemia (T-ALL): A Phase I trial with correlative biology to evaluate a novel chimeric antigen receptor T-cell against CD38 (CART38) in paediatric patients with relapsed or refractory T-ALL
  • 批准号：
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  • 项目类别：
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  • 资助金额：
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  • 财政年份：
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