Presidential Young Investigator: New Methods of Stereochemical Control

罗伯特·汉森博士被授予合成有机化学计划颁发的总统青年研究人员奖，以支持他从实验和理论角度发展立体化学控制的研究。这项工作将提供合成农业和工业所需的新一代分子所需的信息。汉森博士是第一位来自本科生学院(RUI)的化学校长青年研究员。这项研究将包括：(1)用于合成的高立体选择性试剂的开发；(2)“试剂选择性”的直接预测和描述方法的开发；“底物选择性”和“试剂控制”，(3)开发用于动力学拆分对映体的试剂设计的合理方法，(4)将“乘性”反应模型扩展到涉及两个以上手性组分的情况，(5)开发和使用富含对映体的试剂，以提高对映体纯底物反应的区域选择性，以及(6)开发立体选择性反应的构象类似物。

Dr. Robert Hanson is being given the Presidential Young Investigator Award from the Synthetic Organic Chemistry Program to support his research into the development of stereochemical control from both experimental and theoretical viewpoints. This work will provide the information required to synthesize the new generation of molecules needed by agriculture and industry. Dr. Hanson is the first chemistry Presidential Young Investigator from an undergraduate institution (RUI). The research will include: (1) the development of highly stereoselectice reagents for synthesis, (2) the development of directly predictive as well as descriptive measures of "reagent selectivity", "substrate selectivity", and "reagent control", (3) the development of a rational approach to the design of reagents for the kinetic resolution of enantiomers, (4) the extension of "multiplicative" reaction models to situations involving more than two chiral components, (5) the development and use of enantiomerically enriched reagents to impart regioselectivity in the reactions of enantiomerically pure substrates, and (6) the development of conformational analogues of stereoselective reactions.