Presidential Young Investigator Award

总统青年研究人员奖旨在支持旨在了解细胞和分子水平上的形态发生机制的研究，即负责将胚胎细胞组织成复杂组织和器官的机制。该研究计划将研究细胞-细胞相互作用和细胞-底物相互作用，以研究多细胞生物早期发育的定向细胞迁移，以及基因表达和细胞分化的调节。该模型系统是透明的海胆胚胎，因此可以在体内监测细胞的迁移。这项研究应该回答关于从未分化的单细胞和小细胞群体发育复杂组织和器官的基本问题。

This Presidential Young Investigator award is to support research aimed at an understandling of morphogenetic mechanisms at the cellular and molecular levels, that is the mechanisms responsible for organizing embryonic cells into complex tissues and organs. The research program will examine cell-cell interactions and cell-substrate interactions to study the directional cell migrations that characterize the early development of multicellular organisms and the regulation of gene expression and cell differentiation. The model system is the sea urchin embryo which is transparent, thus cell migration may be monitored in vivo. This research should answer fundamental questions about the development of complex tissues and organs from undifferentiated single cell and small cell populations.