Identification of biomarkers associated to sensitivity and resistance of human cancer cell lines to a vaccinia oncolytic virus

与人类癌细胞系对牛痘溶瘤病毒的敏感性和耐药性相关的生物标志物的鉴定

• 批准号: 182343
• 负责人: Perez Iratxeta Carolina
• 金额: $ 5.9万
• 依托单位: Ottawa Hospital Research Institute
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-03-01 至 2010-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=182343&lang=en
• 关键词: Bioinformatics And Biostatistics; Biomarkers Detection; Cancer Therapy; Data Integration; High Througput Data Mining; Oncolytic Virus

An oncolytic virus is a viral strain that has been engineered to selectively infect and destroy cancer cells. Pre-clinical studies on virus JX-594 (a vaccinia-derived oncolytic virus) show promise that it could be effective in treating a wide array of can

溶瘤病毒是一种病毒株，它被设计成选择性地感染和破坏癌细胞。对病毒JX-594（一种牛痘衍生的溶瘤病毒）的临床前研究显示，它可能有效治疗多种癌症。