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Measuring G protein-coupled receptor signaling in vivo with resonance energy-based biosensors

Measuring G protein-coupled receptor signaling in vivo with resonance energy-based biosensors
使用基于共振能量的生物传感器测量体内 G 蛋白偶联受体信号传导
批准号：
365468
负责人：
Jones-Tabah Jace
金额：
$7.65万
依托单位：
McGill University
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2016
资助国家：
加拿大
项目状态：
已结题
起止时间：
2016-10-01 至 2019-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=365468&lang=en
关键词：
Behavioral Pharmacology Biased Agonism/Functional Selectivity Cell Signalling Dopamine Receptor Pharmacology Fiber Photometry G Protein-Coupled Receptors In Vivo Imaging

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英文摘要
G protein-coupled receptors (GPCRs) are proteins that modulate cellular function in response to being activated by hormones, neurotransmitters or drugs. The intracellular signal produced by a given GPCR is highly context dependent. Different physiological
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