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Mechanisms underlying circadian secretion of the anti-diabetic hormone, glucagon-like peptide-1: therapeutic potential

Mechanisms underlying circadian secretion of the anti-diabetic hormone, glucagon-like peptide-1: therapeutic potential
抗糖尿病激素胰高血糖素样肽-1 昼夜节律分泌的机制:治疗潜力
批准号:
355983
负责人:
Brubaker Patricia L
金额:
$55.73万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-10-01 至 2021-10-01

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中文摘要
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英文摘要
The intestinal hormone, glucagon-like peptide-1 (GLP1), is commonly used to reduce blood sugar levels in patients with type 2 diabetes. We have recently discovered that GLP1 levels in the blood change differently between day and night following identical
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Mechanisms dictating the actions of glucagon-like peptide-2, a unique therapeutic for intestinal disorders
  • 批准号:
    344098
  • 项目类别:
    Operating Grants
  • 资助金额:
    $55.69万
  • 财政年份:
    2016
  • 负责人:
    Brubaker Patricia L
  • 依托单位:
Canada Research Chair Tier 1
  • 批准号:
    315385
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2014
  • 负责人:
    Brubaker Patricia L
  • 依托单位:
Interactions between glucagon-like peptide-2 and intestinal insulin-like growth factor-1 signalling in the regulation of intestinal growth and function
  • 批准号:
    253179
  • 项目类别:
    Operating Grants
  • 资助金额:
    $41.6万
  • 财政年份:
    2012
  • 负责人:
    Brubaker Patricia L
  • 依托单位:
Role and mechanism of action of the intestinotrophic hormone, glucagon-like peptide-2, in colonic growth and neoplasia
  • 批准号:
    183255
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.24万
  • 财政年份:
    2008
  • 负责人:
    Brubaker Patricia L
  • 依托单位:
海外基金