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Investigating the role of amyloid beta, oxidative stress, and mitochondrial dysfunction in pre-symptomatic Alzheimer's disease

Investigating the role of amyloid beta, oxidative stress, and mitochondrial dysfunction in pre-symptomatic Alzheimer's disease
研究β淀粉样蛋白、氧化应激和线粒体功能障碍在阿尔茨海默病症状前的作用
批准号：
365464
负责人：
Foret Morgan
金额：
$7.65万
依托单位：
McGill University
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2016
资助国家：
加拿大
项目状态：
已结题
起止时间：
2016-10-01 至 2019-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=365464&lang=en
关键词：
Alzheimer'S Disease Early Amyloid Pathology Ex-Vivo Imaging Intracellular Amyloid Beta Mitochondria Dysfunction Novel Ros Detecting Fluorescent Probes Pre-Clinical Stages Primary Neuron Culture Reactive Oxygen Species (Ros) Transgenic Rat Model

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中文摘要
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英文摘要
There are currently no cures nor preventative therapeutics for Alzheimer's disease (AD) which is the leading cause of dementia in the elderly. Clinical symptoms of AD including memory loss, appear late in the disease progression. Therefore, it is critical
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Elucidating the role of reactive oxygen species (ROS) in the progression of Alzheimer’s Disease (AD) using a transgenic rat model
  • 批准号：
    349956
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $1.27万
  • 财政年份：
    2015
  • 负责人：
    Foret Morgan
  • 依托单位：
    McGill University
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