EMBO Workshop on Spliceosome Assembly and Alternative RNA Splicing, September 2-6, 1990, Bandol, France

九月份将在法国举行一个题为剪接体组装和替代RNA剪接的研讨会。这次会议由欧洲分子生物学组织（EMBO）主办，参加人数将限制在70-90人，其中至少一半是美国人。多种细胞和病毒基因依赖于可选择剪接的调节程序来进行适当的组织和阶段特异性基因表达。本次会议将重点关注调控选择性剪接的分子机制，因此，这是第一次致力于这一重要水平的基因调控。在了解一些特定系统中选择性剪接的生物化学方面，目前正在取得快速的初步进展。会议的三个会议将集中讨论剪接位点选择的新进展，四个会议将讨论病毒和细胞基因中选择性剪接的机制。会议将以一个关于建立组织特异性剪接提取物的实际方面的研讨会结束，以便该系统可以在体外研究和操作。

A workshop entitled Spliceosome Assembly and Alternative RNA Splicing will be held in France in September. The meeting is being organized under the aegis of the European Molecular Biology Organization (EMBO) and will be limited to 70-90 participants, at least half of whom will be Americans. A great variety of cellular and viral genes rely on a regulated program of alternative splicing for appropriate tissue and stage-specific gene expression. This meeting will focus on the molecular mechanisms of regulated alternative splicing and, as such, is the first to be devoted to this important level of gene regulation. Rapid preliminary progress is now being made in understanding the biochemistry of alternative splicing in a number of specific systems. Three sessions of the meeting will focus on new developments in splice site selection and four sessions will deal with the mechanisms of alternative splicing in viruses and cellular genes. The meeting will end with a workshop on practical aspects of establishing tissue-specific splicing extracts, so that the systems can be studied and manipulated in vitro.