Palmitoylation-dependent mTOR signaling in neurodevelopmental disorders
Palmitoylation-dependent mTOR signaling in neurodevelopmental disorders
批准号:
361692
负责人:
Sanders Shaun S
金额:
$10.93万
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-11-01 至 2019-11-01
中文摘要
一种叫做mTOR(雷帕霉素的机制靶标)的酶是细胞生长和存活的关键调节剂。通常情况下,mTOR会因营养物质而被激活或开启,但在癌症和2型糖尿病患者中,其活性会高于正常水平。
英文摘要
An enzyme called mTOR (mechanistic target of rapamycin) is a key regulator of cellular growth and survival. mTOR is normally activated or turned on in response to nutrients, but its activity is increased above normal levels in cancer and type 2 diabetes.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Regulation of ion channel clustering at the axon initial segment by palmitoylation
-
批准号:477701
-
项目类别:Operating Grants
-
资助金额:$58.89万
-
财政年份:2023
-
负责人:Sanders Shaun S
-
依托单位:
The Role of Palmitoylation in Huntington Disease
-
批准号:195929
-
项目类别:Studentship Programs
-
资助金额:$0.0万
-
财政年份:2009
-
负责人:Sanders Shaun S
-
依托单位:
The Role of Palmitoylation of Synaptic Proteins in the Pathogenesis of Huntington Disease
-
批准号:183189
-
项目类别:Studentship Programs
-
资助金额:$1.27万
-
财政年份:2009
-
负责人:Sanders Shaun S
-
依托单位:
海外基金