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Palmitoylation-dependent mTOR signaling in neurodevelopmental disorders

Palmitoylation-dependent mTOR signaling in neurodevelopmental disorders
神经发育障碍中棕榈酰化依赖性 mTOR 信号传导
批准号:
361692
负责人:
Sanders Shaun S
金额:
$10.93万
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-11-01 至 2019-11-01

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中文摘要
翻译
一种叫做mTOR(雷帕霉素的机制靶标)的酶是细胞生长和存活的关键调节剂。通常情况下,mTOR会因营养物质而被激活或开启,但在癌症和2型糖尿病患者中,其活性会高于正常水平。
英文摘要
An enzyme called mTOR (mechanistic target of rapamycin) is a key regulator of cellular growth and survival. mTOR is normally activated or turned on in response to nutrients, but its activity is increased above normal levels in cancer and type 2 diabetes.
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会议论文
Regulation of ion channel clustering at the axon initial segment by palmitoylation
  • 批准号:
    477701
  • 项目类别:
    Operating Grants
  • 资助金额:
    $58.89万
  • 财政年份:
    2023
  • 负责人:
    Sanders Shaun S
  • 依托单位:
The Role of Palmitoylation in Huntington Disease
The Role of Palmitoylation of Synaptic Proteins in the Pathogenesis of Huntington Disease
海外基金