Analysis and Optimization of Mycelial Fermentors

拟议的研究将表征气液质量 菌丝体发酵转移及反应器优化 利用模型菌丝体发酵的性能。 一 一种新的化学质量测量技术 传递系数将被用来表征 气液传质 一种非稳态化学物质 利用瞬时反应的技术， 臭氧和靛蓝染料已经被开发出来， 适用于模拟菌丝体发酵，因为 离子强度低，易于数据收集， 分析. 生物学阶段将采用 纤维素纤维，其在悬浮液中的行为类似于 菌丝生长 该模型系统将用于表征气体- 作为搅拌器速度的函数的液体质量传递， 在各种不同的条件下， 搅拌反应器 涡轮机搅拌器的更换 具有显著的工业价值 主要是由于节能和较低的剪切力 菌丝体肉汤的暴露。 葡萄糖的反应 尼日尔曲霉转化葡萄糖酸的研究将在 最有前途的反应堆配置，以确定是否 气液传质的改进转化为 转化为菌丝体反应器性能的改进。

The proposed research will characterize gas-liquid mass transfer in mycelial fermentations and optimize reactor performance utilizing a model mycelial fermentation. A new chemical technique for the measurement of mass transfer coefficient will be utilized to characterize the gas-liquid mass transfer. An unsteady-state chemical technique utilizing an instantaneous reaction between ozone and indigo dye has been developed and is well- suited for modelling mycelial fermentations because of low ionic strengths and ease of data collection and analysis. The biological phase will be modeled with cellulose fibers, which in suspension behave similarly to mycelular growths. This model system will be used to characterize the gas- liquid mass transfer as a function of stirrer speed, gassing rate and solids concentration in a variety of agitated reactors. The replacement of turbine agitators with hydrofoil impellers has significant industrial interest, primarily due to energy savings and lower shear exposure for the mycelial broth. The reaction of glucose to gluconic acid by Aspergillus niger will be carried out in the most promising reactor configurations to determine if the improvements in gas-liquid mass transfer translate into improvements in the mycelular reactor performance.